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α-MSH (11-13) (free acid)

CAS No.
67727-97-3
Chemical Name:
α-MSH (11-13) (free acid)
Synonyms
KPV;msh(11-13;ACTH-(11-13);H-Lys-Pro-Val-OH;ALPHA-MSH (11-13);α-MSH(11-13)[pig];α-MSH(11-13)[human];H-LYS-PRO-VAL-OH ACOH;α-Melanotropin(11-13);alpha-MSH(11-13) acetate
CBNumber:
CB1241534
Molecular Formula:
C16H30N4O4
Molecular Weight:
342.43
MDL Number:
MFCD00804591
MOL File:
67727-97-3.mol
MSDS File:
SDS
Last updated:2024-01-23 11:29:07

α-MSH (11-13) (free acid) Properties

storage temp. -15°C
InChI InChI=1S/C16H30N4O4/c1-10(2)13(16(23)24)19-14(21)12-7-5-9-20(12)15(22)11(18)6-3-4-8-17/h10-13H,3-9,17-18H2,1-2H3,(H,19,21)(H,23,24)/t11-,12-,13-/m0/s1
InChIKey YSPZCHGIWAQVKQ-AVGNSLFASA-N
SMILES C(O)(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)N

α-MSH (11-13) (free acid) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation PRO0001392 ALPHA-MSH (11-13) ACETATE SALT 95.00% 67727-97-3 5MG $504.86 2021-12-16 Buy
AHH MT-19210 alpha-Msh(11-13)(freeacid)acetatesalt 98% 67727-97-3 0.25g $898 2021-12-16 Buy
Product number Packaging Price Buy
PRO0001392 5MG $504.86 Buy
MT-19210 0.25g $898 Buy

α-MSH (11-13) (free acid) Chemical Properties,Uses,Production

Definition

ChEBI: Lys-Pro-Val is an oligopeptide.

Biological Activity

The C-terminal tripeptide α-MSH(11–13), also known as KPV (L-Lys-L-Pro-L-Val), exhibited anti-inflammation without induction of cutaneous pigmentation in a frog skin bioassay. The underlying molecular mechanisms of the α-MSH(11–13) anti-inflammatory properties have not been determined in detail. However, they are related to an inhibition of TNF-α, IL-6, and nitric oxide production in a model of LPS-stimulated murine microglial cell culture[1]. Furthermore, it has been recently shown that α-MSH(11–13) reduces activation of NF-κB and decreases its translocation into the nucleus by interaction with importin family proteins.

References

[1] Eva-Verena Schaible. “Single administration of tripeptide α-MSH(11-13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice.” PLoS ONE (2013): e71056.

α-MSH (11-13) (free acid) Preparation Products And Raw materials

Raw materials

Preparation Products

α-MSH (11-13) (free acid) Suppliers

Global( 66)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Weimiao Import and Export Trade Co., Ltd.
+undefined19948166995 sale01@hbweimiao.com China 73 58
Hebei Xunou new energy Technology Co., LTD
+undefined17531957005 xunou8@hbxunou.com China 36 58
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152 Mandy@hangyubiotech.com China 11013 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109 xinshengkeji@xsmaterial.com China 1100 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Hebei Anlijie Biotechnology Co., Ltd
+8619031013551 ably@aljbio.com China 180 58
Shijiazhuang Saixin Technology Co., Ltd.
+86-16632312509 +86-16632315022 saixinkeji@aliyun.com China 90 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Sigma Audley
+86-18336680971 +86-18126314766 nova@sh-teruiop.com China 525 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15957 58

View Lastest Price from α-MSH (11-13) (free acid) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ALPHA-MSH (11-13) ACETATE SALT pictures 2024-05-10 ALPHA-MSH (11-13) ACETATE SALT
67727-97-3
US $85.00-850.00 / KG 1KG 0.99 20 tons Zibo Hangyu Biotechnology Development Co., Ltd
KPV pictures 2024-04-25 KPV
67727-97-3
US $50.00 / box 1box >99% 20tons Hong Kong Excellence Biotechnology Co., Ltd.
KPV pictures 2024-04-23 KPV
67727-97-3
US $80.00-75.00 / Box 1Box 99% 66666 Hebei Weimiao Import and Export Trade Co., Ltd.
  • KPV pictures
  • KPV
    67727-97-3
  • US $50.00 / box
  • >99%
  • Hong Kong Excellence Biotechnology Co., Ltd.
  • KPV pictures
  • KPV
    67727-97-3
  • US $80.00-75.00 / Box
  • 99%
  • Hebei Weimiao Import and Export Trade Co., Ltd.
α-Melanotropin(11-13) α-Melanotropin(11-13)[human] α-Melanotropin(11-13)[pig] α-MSH(11-13)[human] α-MSH(11-13)[pig] a-MSH (11-13) (free acid) H-LYS-PRO-VAL-OH ACETATE SALT H-LYS-PRO-VAL-OH ACOH ALPHA-MSH (11-13) ALPHA-MSH (11-13) ACETATE SALT msh(11-13 .alpha.-MSH (11-13) (free acid) H-Lys-Pro-Val-OH alpha-Msh (11-13) (free acid) acetate salt L-Valine, L-lysyl-L-prolyl- α-MSH (11-13) (free acid) ACTH-(11-13) (2S)-2-[[(2S)-1-[(2S)-2,6-diaminohexanoyl]pyrrolidine-2-carbonyl]amino]-3-methylbutanoic acid alpha-MSH(11-13) acetate KPV KPV (α-MSH (11-13) (free acid) KPV,ALPHA-MSH (11-13) ACETATE SALT α-MSH (11-13) (free acid) acetate salt 67727-97-3 C16H30N4O4C2H4O2